该剧改编自藤萍的小说《吉祥纹莲花楼》。十年前四顾门门主李相夷以相夷太剑冠绝天下，为正道武林之光，却因与金鸳盟盟主笛飞声约战东海，两大高手就此消失在万顷碧波之上。四顾门与金鸳盟也两败俱伤渐渐消失于江湖。十年后乡间游医李莲花拖着一座莲花楼行走世间，误打误撞得了个名医的头衔，本不想涉足江湖的他就这样卷入江湖。梦想行侠仗义安天下的热血少爷方多病则察觉李莲花不简单，于是誓要找出李莲花假冒名医的罪证，而一直将李相夷视为劲敌的笛飞声，在重出江湖后认出不起眼的游医李莲花就是李相宜，又怎能轻易放过。经过一系列案件，三人竟在嬉笑怒骂的破案过程中结下了深厚的友谊。本已无心江湖事的李莲花和笛飞声在以天下安危为己任的少年方多病的带动下也重新燃起热血豪情，三人携手战斗，共破江湖奇案，还天下正义和太平。
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It is a story of a mistress who comes back for her revenge after enduring all kinds of mistreats from her husband's wedded wife. The resentment between two love rivals is passed on to their descents and grows into a war between two bloodlines. Onnapa is a mistress of a millionaire who owns the biggest flower business in the country. She has endured all kinds of mistreats by her husband's lawful life, Kannika, for years. When their husband dies, Kannika kicked Onnapa out of their home. Onnapa is enraged by the injustice and furious at Kannika. Although more than 30 years have passed, the resentment in Onnapa's heart has never eased off. Now, it is passed on to her daughter and grandchildren. Along with her daughter - Onsalao and her grandsons - Worakorn and Worawet, Onnapa comes back to take her revenge and reclaim things that should have been hers. Onnapa starts a war with Kannika and her descents including Kannika's daughter - Thantawan, and her grandchildren - Mintra, Nonsee, and Iris. Filled with trickery, deceit, and betrayal, how will this war end?
